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Additional cytosine inside mitochondrial C-tract D-loop as a progression risk factor in oral precancer cases
INTRODUCTION: Alterations inside Polycytosine tract (C-tract) of mitochondrial DNA (mtDNA) have been described in many different tumor types. The Poly-Cytosine region is located within the mtDNA D-loop region which acts as point of mitochondrial replication origin. A suggested pathogenesis is that i...
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Publicado no: | J Oral Biol Craniofac Res |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4252640/ https://ncbi.nlm.nih.gov/pubmed/25737911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jobcr.2014.02.003 |
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