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Additional cytosine inside mitochondrial C-tract D-loop as a progression risk factor in oral precancer cases

INTRODUCTION: Alterations inside Polycytosine tract (C-tract) of mitochondrial DNA (mtDNA) have been described in many different tumor types. The Poly-Cytosine region is located within the mtDNA D-loop region which acts as point of mitochondrial replication origin. A suggested pathogenesis is that i...

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Detalhes bibliográficos
Publicado no:J Oral Biol Craniofac Res
Main Authors: Pandey, Rahul, Mehrotra, Divya, Mahdi, Abbas Ali, Sarin, Rajiv, Kowtal, Pradnya
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252640/
https://ncbi.nlm.nih.gov/pubmed/25737911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jobcr.2014.02.003
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