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A protein tagging system for signal amplification in gene expression and fluorescence imaging

Signals in many biological processes can be amplified by recruiting multiple copies of regulatory proteins to a site of action. Harnessing this principle, we have developed a novel protein scaffold, a repeating peptide array termed SunTag, which can recruit multiple copies of an antibody-fusion prot...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Tanenbaum, Marvin E., Gilbert, Luke A., Qi, Lei S., Weissman, Jonathan S., Vale, Ronald D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252608/
https://ncbi.nlm.nih.gov/pubmed/25307933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.09.039
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