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Oxidative Halogenation of Cisplatin and Carboplatin: Synthesis, Spectroscopy, and Crystal and Molecular Structures of Pt(IV) Prodrugs

A series of Pt(IV) prodrugs has been obtained by oxidative halogenation of either cisplatin or carboplatin. Iodobenzene dichloride is a general reagent that cleanly provides prodrugs bearing axial chlorides without the need to prepare intervening Pt(IV) intermediates or handle chlorine gas. Elementa...

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Bibliografiska uppgifter
I publikationen:Dalton Trans
Huvudupphovsmän: Johnstone, Timothy C., Alexander, Sarah M., Wilson, Justin J., Lippard, Stephen J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252584/
https://ncbi.nlm.nih.gov/pubmed/25367395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4dt02627f
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