Impairment of Glymphatic Pathway Function Promotes Tau Pathology after Traumatic Brain Injury

Traumatic brain injury (TBI) is an established risk factor for the early development of dementia, including Alzheimer's disease, and the post-traumatic brain frequently exhibits neurofibrillary tangles comprised of aggregates of the protein tau. We have recently defined a brain-wide network of...

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Publicado en:J Neurosci
Autores principales: Iliff, Jeffrey J., Chen, Michael J., Plog, Benjamin A., Zeppenfeld, Douglas M., Soltero, Melissa, Yang, Lijun, Singh, Itender, Deane, Rashid, Nedergaard, Maiken
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2014
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252540/
https://ncbi.nlm.nih.gov/pubmed/25471560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3020-14.2014
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