Mechanisms of fever induced by recombinant human interferon.

Since the early trials using human interferon (hIFN) derived from blood leukocytes or cell lines, fever has been a prominent component of IFN therapy. Human protein impurities might account for the fever to cell-derived hIFN, but recombinant hIFN, free of extraneous human proteins, has produced feve...

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Main Authors: Dinarello, C A, Bernheim, H A, Duff, G W, Le, H V, Nagabhushan, T L, Hamilton, N C, Coceani, F
Formato: Artigo
Idioma:Inglês
Publicado: 1984
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC425246/
https://ncbi.nlm.nih.gov/pubmed/6590569
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