Bepridil and cetiedil. Vasodilators which inhibit Ca2+-dependent calmodulin interactions with erythrocyte membranes.

Two new vascular smooth muscle relaxants, bepridil and cetiedil, were found to possess specific CaM-inhibitory properties which resembled those of trifluoperazine. Trifluoperazine, bepridil, and cetiedil inhibited Ca2+-dependent 125I-CaM binding to erythrocyte membranes and CaM activation of membran...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Agre, P, Virshup, D, Bennett, V
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1984
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425235/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6088585/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111497
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