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Bepridil and cetiedil. Vasodilators which inhibit Ca2+-dependent calmodulin interactions with erythrocyte membranes.

Two new vascular smooth muscle relaxants, bepridil and cetiedil, were found to possess specific CaM-inhibitory properties which resembled those of trifluoperazine. Trifluoperazine, bepridil, and cetiedil inhibited Ca2+-dependent 125I-CaM binding to erythrocyte membranes and CaM activation of membran...

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Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Agre, P, Virshup, D, Bennett, V
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 1984
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425235/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6088585/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111497
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