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Osteoblast-Specific Deletion of Pkd2 Leads to Low-Turnover Osteopenia and Reduced Bone Marrow Adiposity

Polycystin-1 (Pkd1) interacts with polycystin-2 (Pkd2) to form an interdependent signaling complex. Selective deletion of Pkd1 in the osteoblast lineage reciprocally regulates osteoblastogenesis and adipogenesis. The role of Pkd2 in skeletal development has not been defined. To this end, we conditio...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Xiao, Zhousheng, Cao, Li, Liang, Yingjuan, Huang, Jinsong, Stern, Amber Rath, Dallas, Mark, Johnson, Mark, Quarles, Leigh Darryl
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252138/
https://ncbi.nlm.nih.gov/pubmed/25464512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114198
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