HIV-1 Infection Causes a Down-Regulation of Genes Involved in Ribosome Biogenesis

HIV-1 preferentially infects CD4(+) T cells, causing fundamental changes that eventually lead to the release of new viral particles and cell death. To investigate in detail alterations in the transcriptome of the CD4(+) T cells upon viral infection, we sequenced polyadenylated RNA isolated from Jurk...

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Publicat a:PLoS One
Autors principals: Kleinman, Claudia L., Doria, Margherita, Orecchini, Elisa, Giuliani, Erica, Galardi, Silvia, De Jay, Nicolas, Michienzi, Alessandro
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252078/
https://ncbi.nlm.nih.gov/pubmed/25462981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113908
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