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Coagulation factor Va binds to human umbilical vein endothelial cells and accelerates protein C activation.

In vitro the rate of protein C activation by thrombin is significantly accelerated by two distinct cofactors (a) the endothelial cell surface protein, thrombomodulin, and (b) human coagulation Factor Va. We have recently reported that the activity of Factor Va is contained in the 78,000-D light chai...

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Библиографические подробности
Опубликовано в::J Clin Invest
Главные авторы: Maruyama, I, Salem, H H, Majerus, P W
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1984
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425204/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6547457/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111405
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