CFS-1686 Causes Cell Cycle Arrest at Intra-S Phase by Interference of Interaction of Topoisomerase 1 with DNA

CFS-1686 (chemical name (E)-N-(2-(diethylamino)ethyl)-4-(2-(2-(5-nitrofuran-2-yl)vinyl)quinolin-4-ylamino)benzamide) inhibits cell proliferation and triggers late apoptosis in prostate cancer cell lines. Comparing the effect of CFS-1686 on cell cycle progression with the topoisomerase 1 inhibitor ca...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lin, Ru-Wei, Yang, Chia-Ning, Ku, ShengYu, Ho, Cheng-Jung, Huang, Shih-Bo, Yang, Min-Chi, Chang, Hsin-Wen, Lin, Chun-Mao, Hwang, Jaulang, Chen, Yeh-Long, Tzeng, Cherg-Chyi, Wang, Chihuei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252032/
https://ncbi.nlm.nih.gov/pubmed/25460368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113832
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