TGF-β1/Smad Signaling Pathway Regulates Epithelial-to-Mesenchymal Transition in Esophageal Squamous Cell Carcinoma: In Vitro and Clinical Analyses of Cell Lines and Nomadic Kazakh Patients from Northwest Xinjiang, China

Invasion and metastasis are the major causes of death in patients with esophageal squamous cell carcinoma (ESCC). Epithelial-mesenchymal transition (EMT) is a critical step in tumor progression and transforming growth factor-β1 (TGF-β1) signaling has been shown to play an important role in EMT. In t...

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Udgivet i:PLoS One
Main Authors: Pang, Lijuan, Li, Qiuxiang, Wei, Cuilei, Zou, Hong, Li, Shugang, Cao, Weiwei, He, Jianwei, Zhou, Yang, Ju, Xinxin, Lan, Jiaojiao, Wei, Yutao, Wang, Chengyan, Zhao, Wei, Hu, Jianming, Jia, Wei, Qi, Yan, Liu, Fudong, Jiang, Jinfang, Li, Li, Zhao, Jin, Liang, Weihua, Xie, Jianxin, Li, Feng
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251902/
https://ncbi.nlm.nih.gov/pubmed/25464508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112300
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