TGF-β1/Smad Signaling Pathway Regulates Epithelial-to-Mesenchymal Transition in Esophageal Squamous Cell Carcinoma: In Vitro and Clinical Analyses of Cell Lines and Nomadic Kazakh Patients from Northwest Xinjiang, China

Invasion and metastasis are the major causes of death in patients with esophageal squamous cell carcinoma (ESCC). Epithelial-mesenchymal transition (EMT) is a critical step in tumor progression and transforming growth factor-β1 (TGF-β1) signaling has been shown to play an important role in EMT. In t...

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Veröffentlicht in:PLoS One
Hauptverfasser: Pang, Lijuan, Li, Qiuxiang, Wei, Cuilei, Zou, Hong, Li, Shugang, Cao, Weiwei, He, Jianwei, Zhou, Yang, Ju, Xinxin, Lan, Jiaojiao, Wei, Yutao, Wang, Chengyan, Zhao, Wei, Hu, Jianming, Jia, Wei, Qi, Yan, Liu, Fudong, Jiang, Jinfang, Li, Li, Zhao, Jin, Liang, Weihua, Xie, Jianxin, Li, Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251902/
https://ncbi.nlm.nih.gov/pubmed/25464508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112300
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