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CPSI-121 pharmacologically prevents intestinal barrier dysfunction after cutaneous burn through a vagus nerve-dependent mechanism

BACKGROUND: We have recently demonstrated the protective effects of electrical stimulation of the vagus nerve in prevention of gut injury after severe burn. Here we evaluate the potential for a pharmacologic agonist of the vagus nerve as an approach to regulate outcomes in preclinical models. We tes...

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Detalhes bibliográficos
Publicado no:J Trauma Acute Care Surg
Main Authors: Krzyzaniak, Michael, Ortiz-Pomales, Yan, Lopez, Nicole, Reys, Luiz Guilherme, Cheadle, Gerald, Wolf, Paul, Eliceiri, Brian, Bansal, Vishal, Baird, Andrew, Coimbra, Raul
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251782/
https://ncbi.nlm.nih.gov/pubmed/22327977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0b013e31824484fe
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