CPSI-121 pharmacologically prevents intestinal barrier dysfunction after cutaneous burn through a vagus nerve-dependent mechanism

BACKGROUND: We have recently demonstrated the protective effects of electrical stimulation of the vagus nerve in prevention of gut injury after severe burn. Here we evaluate the potential for a pharmacologic agonist of the vagus nerve as an approach to regulate outcomes in preclinical models. We tes...

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Vydáno v:J Trauma Acute Care Surg
Hlavní autoři: Krzyzaniak, Michael, Ortiz-Pomales, Yan, Lopez, Nicole, Reys, Luiz Guilherme, Cheadle, Gerald, Wolf, Paul, Eliceiri, Brian, Bansal, Vishal, Baird, Andrew, Coimbra, Raul
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251782/
https://ncbi.nlm.nih.gov/pubmed/22327977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0b013e31824484fe
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