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Carrier detection of Hemophilia B by using a restriction site polymorphism associated with the coagulation Factor IX gene.

The cloned complementary DNA for coagulation Factor IX (FIX) detects a frequent restriction fragment length polymorphism (RFLP) in human genomic DNAs digested with the restriction endonuclease Taq I. This genetic marker was used, in parallel with coagulation and immunological assays, to follow the s...

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Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Grunebaum, L, Cazenave, J P, Camerino, G, Kloepfer, C, Mandel, J L, Tolstoshev, P, Jaye, M, De la Salle, H, Lecocq, J P
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1984
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425173/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6325506/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111354
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