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Retinoblastoma gene product as a downstream target for a ceramide-dependent pathway of growth arrest.

Ceramide, a lipid mediator, has been most closely associated with antiproliferative activities. In this study, we examine the mechanism by which ceramide induces growth suppression and the role of the retinoblastoma gene product (Rb) in this process. Withdrawal of serum from the serum-dependent MOLT...

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Hlavní autoři: Dbaibo, G S, Pushkareva, M Y, Jayadev, S, Schwarz, J K, Horowitz, J M, Obeid, L M, Hannun, Y A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1995
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC42516/
https://ncbi.nlm.nih.gov/pubmed/7877980
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