p53-mediated cellular response to DNA damage in cells with replicative hepatitis B virus.

Wild-type p53 acts as a tumor suppressor gene by protecting cells from deleterious effects of genotoxic agents through the induction of a G1/S arrest or apoptosis as a response to DNA damage. Transforming proteins of several oncogenic DNA viruses inactivate tumor suppressor activity of p53 by blocki...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Puisieux, A, Ji, J, Guillot, C, Legros, Y, Soussi, T, Isselbacher, K, Ozturk, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42515/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7877979/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.5.1342
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