Intracisternal delivery of NFκB-inducible scAAV2/9 reveals locoregional neuroinflammation induced by systemic kainic acid treatment

We have previously demonstrated disease-dependent gene delivery in the brain using an AAV vector responding to NFκB activation as a probe for inflammatory responses. This vector, injected focally in the parenchyma prior to a systemic kainic acid (KA) injection mediated inducible transgene expression...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Bockstael, Olivier, Tenenbaum, Liliane, Dalkara, Deniz, Melas, Catherine, De Witte, Olivier, Levivier, Marc, Chtarto, Abdelwahed
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251317/
https://ncbi.nlm.nih.gov/pubmed/25520614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00092
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