The stem cell organisation, and the proliferative and gene expression profile of Barrett's epithelium, replicates pyloric-type gastric glands

OBJECTIVE: Barrett's oesophagus shows appearances described as ‘intestinal metaplasia’, in structures called ‘crypts’ but do not typically display crypt architecture. Here, we investigate their relationship to gastric glands. METHODS: Cell proliferation and migration within Barrett's gland...

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Vydáno v:Gut
Hlavní autoři: Lavery, Danielle L, Nicholson, Anna M, Poulsom, Richard, Jeffery, Rosemary, Hussain, Alia, Gay, Laura J, Jankowski, Janusz A, Zeki, Sebastian S, Barr, Hugh, Harrison, Rebecca, Going, James, Kadirkamanathan, Sritharan, Davis, Peter, Underwood, Timothy, Novelli, Marco R, Rodriguez–Justo, Manuel, Shepherd, Neil, Jansen, Marnix, Wright, Nicholas A, McDonald, Stuart A C
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2014
Témata:
Oesophagus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251192/
https://ncbi.nlm.nih.gov/pubmed/24550372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-306508
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