The stem cell organisation, and the proliferative and gene expression profile of Barrett's epithelium, replicates pyloric-type gastric glands

OBJECTIVE: Barrett's oesophagus shows appearances described as ‘intestinal metaplasia’, in structures called ‘crypts’ but do not typically display crypt architecture. Here, we investigate their relationship to gastric glands. METHODS: Cell proliferation and migration within Barrett's gland...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Lavery, Danielle L, Nicholson, Anna M, Poulsom, Richard, Jeffery, Rosemary, Hussain, Alia, Gay, Laura J, Jankowski, Janusz A, Zeki, Sebastian S, Barr, Hugh, Harrison, Rebecca, Going, James, Kadirkamanathan, Sritharan, Davis, Peter, Underwood, Timothy, Novelli, Marco R, Rodriguez–Justo, Manuel, Shepherd, Neil, Jansen, Marnix, Wright, Nicholas A, McDonald, Stuart A C
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2014
Assuntos:
Oesophagus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251192/
https://ncbi.nlm.nih.gov/pubmed/24550372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-306508
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