Isolation of Pyrrolocins A–C: cis- and trans-Decalin Tetramic Acid Antibiotics from an Endophytic Fungal-Derived Pathway

[Image: see text] Three new decalin-type tetramic acid analogues, pyrrolocins A (1), B (2), and C (3), were defined as products of a metabolic pathway from a fern endophyte, NRRL 50135, from Papua New Guinea. NRRL 50135 initially produced 1 but ceased its production before chemical or biological eva...

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Publicat a:J Nat Prod
Autors principals: Jadulco, Raquel C., Koch, Michael, Kakule, Thomas B., Schmidt, Eric W., Orendt, Anita, He, Haiyin, Janso, Jeffrey E., Carter, Guy T., Larson, Erica C., Pond, Christopher, Matainaho, Teatulohi K., Barrows, Louis R.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society and American Society of Pharmacognosy 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251065/
https://ncbi.nlm.nih.gov/pubmed/25351193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np500617u
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