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Native Promoter Strategy for High-Yielding Synthesis and Engineering of Fungal Secondary Metabolites

[Image: see text] Strategies are needed for the robust production of cryptic, silenced, or engineered secondary metabolites in fungi. The filamentous fungus Fusarium heterosporum natively synthesizes the polyketide equisetin at >2 g L(–1) in a controllable manner. We hypothesized that this produc...

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Detalhes bibliográficos
Publicado no:ACS Synth Biol
Main Authors: Kakule, Thomas B., Jadulco, Raquel C., Koch, Michael, Janso, Jeffrey E., Barrows, Louis R., Schmidt, Eric W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487227/
https://ncbi.nlm.nih.gov/pubmed/25226362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/sb500296p
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