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Competitive molecular docking approach for predicting estrogen receptor subtype α agonists and antagonists

BACKGROUND: Endocrine disrupting chemicals (EDCs) are exogenous compounds that interfere with the endocrine system of vertebrates, often through direct or indirect interactions with nuclear receptor proteins. Estrogen receptors (ERs) are particularly important protein targets and many EDCs are ER bi...

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Bibliografiske detaljer
Udgivet i:BMC Bioinformatics
Main Authors: Ng, Hui Wen, Zhang, Wenqian, Shu, Mao, Luo, Heng, Ge, Weigong, Perkins, Roger, Tong, Weida, Hong, Huixiao
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251048/
https://ncbi.nlm.nih.gov/pubmed/25349983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-S11-S4
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