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Expression and immunoactivity of chimeric particulate antigens of receptor binding site-core antigen of hepatitis B virus
AIM: To improve the immunogenicity of receptor binding site of hepatitis B virus (HBV) on preS1 antigen using HBV core antigen as an immuno-carrier. METHODS: One to 6 tandem copies of HBV preS1 (21-47) fragment were inserted into HBcAg at the sites of aa 78 and 82, and expressed in E.coli. ELISA, We...
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| Опубликовано в: : | World J Gastroenterol |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Baishideng Publishing Group Inc
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4250797/ https://ncbi.nlm.nih.gov/pubmed/15641132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i4.492 |
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