Biosynthesis of coagulation Factor V by a human hepatocellular carcinoma cell line.

A human hepatocellular carcinoma line, HepG2, was found to secrete coagulation Factor V. Factor V activity in HepG2 culture fluid increased nearly linearly during a 20-h time course (5 ng Factor Va/h per 10(6) cells). Thrombin treatment increased Factor V activity in HepG2 culture medium six- to nin...

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Bibliographic Details
Main Authors: Wilson, D B, Salem, H H, Mruk, J S, Maruyama, I, Majerus, P W
Format: Artigo
Language:Inglês
Published: 1984
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC425065/
https://ncbi.nlm.nih.gov/pubmed/6200498
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