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Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers
The transport activity of human mitochondrial aspartate/glutamate carriers is central to the malate–aspartate shuttle, urea cycle, gluconeogenesis and myelin synthesis. They have a unique three-domain structure, comprising a calcium-regulated N-terminal domain with eight EF-hands, a mitochondrial ca...
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| Published in: | Nat Commun |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Pub. Group
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4250520/ https://ncbi.nlm.nih.gov/pubmed/25410934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6491 |
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