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Inhibitory effects of a novel Val to Thr mutation on the distal heme of human catalase
True catalases efficiently breakdown hydrogen peroxide, whereas the catalase-related enzyme allene oxide synthase (cAOS) is completely unreactive and instead metabolizes a fatty acid hydroperoxide. In cAOS a Thr residue adjacent to the distal His restrains reaction with H(2)O(2) (Tosha et al (2006)...
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| Publicado no: | Biochimie |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4250446/ https://ncbi.nlm.nih.gov/pubmed/25086217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2014.07.021 |
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