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Role of the conserved distal heme asparagine of coral allene oxide synthase (Asn137) and human catalase (Asn148): mutations affect the rate but not the essential chemistry of the enzymatic transformations

A catalase-related allene oxide synthase (cAOS) and true catalases that metabolize hydrogen peroxide have similar structure around the heme. One of the distal heme residues considered to help control catalysis is a highly conserved asparagine. Here we addressed the role of this residue in metabolism...

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Autori principali: Gao, Benlian, Boeglin, William E., Brash, Alan R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2598388/
https://ncbi.nlm.nih.gov/pubmed/18652800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.07.011
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