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Exendin-4 Improves Cardiac Function in Mice Overexpressing Monocyte Chemoattractant Protein-1 in Cardiomyocytes

The incretin hormone glucagon-like peptide-1 (Glp1) is cardioprotective in models of ischemia-reperfusion injury, myocardial infarction and gluco/lipotoxicity. Inflammation is a factor in these models, yet it is unknown whether Glp1 receptor (Glp1r) agonists are protective against cardiac inflammati...

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Publicat a:J Mol Cell Cardiol
Autors principals: Younce, Craig W., Niu, Jianli, Ayala, Jennifer, Burmeister, Melissa A., Smith, Layton H., Kolattukudy, Pappachan, Ayala, Julio E.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250388/
https://ncbi.nlm.nih.gov/pubmed/25200599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.08.022
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