Hyperglycaemia-induced cardiomyocyte death is mediated via MCP-1 production and induction of a novel zinc-finger protein MCPIP

AIMS: Cardiomyocyte apoptosis contributes to the development of diabetic cardiomyopathy. How the elevated glucose levels associated with diabetes cause cell death is unknown. Here we report that high glucose-induced cardiomyocyte death is mediated via monocyte chemotactic protein-1 (MCP-1) productio...

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Hlavní autoři: Younce, Craig W., Wang, Kangkai, Kolattukudy, Pappachan E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920810/
https://ncbi.nlm.nih.gov/pubmed/20356868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq102
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