Monocyte Chemoattractant Protein-1 Induces a Novel Transcription Factor That Causes Cardiac Myocyte Apoptosis and Ventricular Dysfunction

Monocyte chemoattractant protein-1 (MCP-1; CCL2)–mediated inflammation plays a critical role in the development of ischemic heart disease (IHD). However, the gene expression changes caused by signal transduction, triggered by MCP-1 binding to its receptor CCR2, and their possible role in the develop...

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Détails bibliographiques
Auteurs principaux: Zhou, Limei, Azfer, Asim, Niu, Jianli, Graham, Sarabeth, Choudhury, Mahua, Adamski, Frances M., Younce, Craig, Binkley, Phillip F., Kolattukudy, Pappachan E.
Format: Artigo
Langue:Inglês
Publié: 2006
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1523425/
https://ncbi.nlm.nih.gov/pubmed/16574901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.RES.0000220106.64661.71
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