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Upstream Open Reading Frame in 5′-Untranslated Region Reduces Titin mRNA Translational Efficiency
Titin is the largest known protein and a critical determinant of myofibril elasticity and sarcomere structure in striated muscle. Accumulating evidence that mRNA transcripts are post-transcriptionally regulated by specific motifs located in the flanking untranslated regions (UTRs) led us to consider...
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Pubblicato in: | Biochem Biophys Res Commun |
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Autori principali: | , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2014
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4250383/ https://ncbi.nlm.nih.gov/pubmed/25264194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.09.085 |
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