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Neurite outgrowth induced by NGF or L1CAM via activation of the TrkA receptor is sustained also by the exocytosis of enlargeosomes

NGF binding to its protein kinase receptor TrkA is known to induce neurite outgrowth and neural cell differentiation. The plasma membrane expansion, necessary for the process, was shown to be contributed by the VAMP7-dependent exocytosis of endocytic vesicles. Working with wild-type PC12 (wtPC12), a...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Colombo, Federico, Racchetti, Gabriella, Meldolesi, Jacopo
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250127/
https://ncbi.nlm.nih.gov/pubmed/25385598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406097111
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