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Astrocyte Stellation, a Process Dependent on Rac1 Is Sustained by the Regulated Exocytosis of Enlargeosomes

Cultured astrocytes exhibit a flat/epitelioid phenotype much different from the star-like phenotype of tissue astrocytes. Upon exposure to treatments that affect the small GTPase Rho and/or its effector ROCK, however, flat astrocytes undergo stellation, with restructuring of cytoskeleton and outgrow...

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Autores principales: Racchetti, Gabriella, D'Alessandro, Rosalba, Meldolesi, Jacopo
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306795/
https://ncbi.nlm.nih.gov/pubmed/22144092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22280
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