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Generation of Recombination Activating Gene-1-Deficient Neonatal Piglets: A Model of T and B Cell Deficient Severe Combined Immune Deficiency

Although severe combined immune deficiency (SCID) is a very important research model for mice and SCID mice are widely used, there are only few reports describing the SCID pig models. Therefore, additional research in this area is needed. In this study, we describe the generation of Recombination ac...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ito, Tetsuya, Sendai, Yutaka, Yamazaki, Satoshi, Seki-Soma, Marie, Hirose, Kensuke, Watanabe, Motoo, Fukawa, Kazuo, Nakauchi, Hiromitsu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249935/
https://ncbi.nlm.nih.gov/pubmed/25437445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113833
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