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Comparison of Temporal Transcriptomic Profiles from Immature Lungs of Two Rat Strains Reveals a Viral Response Signature Associated with Chronic Lung Dysfunction

Early life respiratory viral infections and atopic characteristics are significant risk factors for the development of childhood asthma. It is hypothesized that repeated respiratory viral infections might induce structural remodeling by interfering with the normal process of lung maturation; however...

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Veröffentlicht in:PLoS One
Hauptverfasser: Hines, Elizabeth A., Szakaly, Renee J., Leng, Ning, Webster, Anais T., Verheyden, Jamie M., Lashua, Amber J., Kendziorski, Christina, Rosenthal, Louis A., Gern, James E., Sorkness, Ronald L., Sun, Xin, Lemanske, Robert F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249857/
https://ncbi.nlm.nih.gov/pubmed/25437859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112997
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