Comparison of temporal transcriptomic profiles from immature lungs of two rat strains reveals a viral response signature associated with chronic lung dysfunction.

Early life respiratory viral infections and atopic characteristics are significant risk factors for the development of childhood asthma. It is hypothesized that repeated respiratory viral infections might induce structural remodeling by interfering with the normal process of lung maturation; however...

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Main Authors: Elizabeth A Hines, Renee J Szakaly, Ning Leng, Anais T Webster, Jamie M Verheyden, Amber J Lashua, Christina Kendziorski, Louis A Rosenthal, James E Gern, Ronald L Sorkness, Xin Sun, Robert F Lemanske
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2014-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4249857?pdf=render
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