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Transferable Coarse-Grained Potential for De Novo Protein Folding and Design

Protein folding and design are major biophysical problems, the solution of which would lead to important applications especially in medicine. Here we provide evidence of how a novel parametrization of the Caterpillar model may be used for both quantitative protein design and folding. With computer s...

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Bibliografiske detaljer
Udgivet i:PLoS One
Hovedforfatter: Coluzza, Ivan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249799/
https://ncbi.nlm.nih.gov/pubmed/25436908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112852
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