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Transferable Coarse-Grained Potential for De Novo Protein Folding and Design

Protein folding and design are major biophysical problems, the solution of which would lead to important applications especially in medicine. Here we provide evidence of how a novel parametrization of the Caterpillar model may be used for both quantitative protein design and folding. With computer s...

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Библиографические подробности
Опубликовано в: :PLoS One
Главный автор: Coluzza, Ivan
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249799/
https://ncbi.nlm.nih.gov/pubmed/25436908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112852
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