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The role of tyrosine kinases in systemic lupus erythematosus and their potential as therapeutic targets
The autoimmune disease systemic lupus erythematosus is characterized by loss of tolerance to nuclear antigens. Breakdown of tolerance is associated with alterations in T-cell and B-cell receptor signal transduction, including increased protein phosphorylation that may underlie pathogenesis and expla...
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| Vydáno v: | Expert Rev Clin Immunol |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4249585/ https://ncbi.nlm.nih.gov/pubmed/24678775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/1744666X.2014.893827 |
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