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The role of tyrosine kinases in systemic lupus erythematosus and their potential as therapeutic targets

The autoimmune disease systemic lupus erythematosus is characterized by loss of tolerance to nuclear antigens. Breakdown of tolerance is associated with alterations in T-cell and B-cell receptor signal transduction, including increased protein phosphorylation that may underlie pathogenesis and expla...

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Detalhes bibliográficos
Publicado no:Expert Rev Clin Immunol
Main Authors: Shao, Wen-Hai, Cohen, Philip L
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249585/
https://ncbi.nlm.nih.gov/pubmed/24678775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/1744666X.2014.893827
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