Extracellular DNA Impedes the Transport of Vancomycin in Staphylococcus epidermidis Biofilms Preexposed to Subinhibitory Concentrations of Vancomycin

Staphylococcus epidermidis biofilm formation is responsible for the persistence of orthopedic implant infections. Previous studies have shown that exposure of S. epidermidis biofilms to sub-MICs of antibiotics induced an increased level of biofilm persistence. BODIPY FL-vancomycin (a fluorescent van...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Doroshenko, Natalya, Tseng, Boo Shan, Howlin, Robert P., Deacon, Jill, Wharton, Julian A., Thurner, Philipp J., Gilmore, Brendan F., Parsek, Matthew R., Stoodley, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249571/
https://ncbi.nlm.nih.gov/pubmed/25267673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03132-14
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