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Extracellular DNA Impedes the Transport of Vancomycin in Staphylococcus epidermidis Biofilms Preexposed to Subinhibitory Concentrations of Vancomycin

Staphylococcus epidermidis biofilm formation is responsible for the persistence of orthopedic implant infections. Previous studies have shown that exposure of S. epidermidis biofilms to sub-MICs of antibiotics induced an increased level of biofilm persistence. BODIPY FL-vancomycin (a fluorescent van...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Doroshenko, Natalya, Tseng, Boo Shan, Howlin, Robert P., Deacon, Jill, Wharton, Julian A., Thurner, Philipp J., Gilmore, Brendan F., Parsek, Matthew R., Stoodley, Paul
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249571/
https://ncbi.nlm.nih.gov/pubmed/25267673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03132-14
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