Extracellular DNA Impedes the Transport of Vancomycin in Staphylococcus epidermidis Biofilms Preexposed to Subinhibitory Concentrations of Vancomycin

Staphylococcus epidermidis biofilm formation is responsible for the persistence of orthopedic implant infections. Previous studies have shown that exposure of S. epidermidis biofilms to sub-MICs of antibiotics induced an increased level of biofilm persistence. BODIPY FL-vancomycin (a fluorescent van...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Doroshenko, Natalya, Tseng, Boo Shan, Howlin, Robert P., Deacon, Jill, Wharton, Julian A., Thurner, Philipp J., Gilmore, Brendan F., Parsek, Matthew R., Stoodley, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249571/
https://ncbi.nlm.nih.gov/pubmed/25267673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03132-14
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