Sensitization of Intracellular Salmonella enterica Serovar Typhimurium to Aminoglycosides In Vitro and In Vivo by a Host-Targeted Antimicrobial Agent

Aminoglycosides exhibit relatively poor activity against intracellular Salmonella enterica serovar Typhimurium due to their low permeativity across eukaryotic cell membranes. Previously, we identified the unique ability of AR-12, a celecoxib-derived small-molecule agent, to eradicate intracellular S...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Lo, Jung-Hsin, Kulp, Samuel K., Chen, Ching-Shih, Chiu, Hao-Chieh
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249550/
https://ncbi.nlm.nih.gov/pubmed/25267669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03778-14
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