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Sensitization of Intracellular Salmonella enterica Serovar Typhimurium to Aminoglycosides In Vitro and In Vivo by a Host-Targeted Antimicrobial Agent

Aminoglycosides exhibit relatively poor activity against intracellular Salmonella enterica serovar Typhimurium due to their low permeativity across eukaryotic cell membranes. Previously, we identified the unique ability of AR-12, a celecoxib-derived small-molecule agent, to eradicate intracellular S...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Lo, Jung-Hsin, Kulp, Samuel K., Chen, Ching-Shih, Chiu, Hao-Chieh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249550/
https://ncbi.nlm.nih.gov/pubmed/25267669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03778-14
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