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Clinical Validation of the Analysis of Fluconazole in Oral Fluid in Hospitalized Children

Fluconazole is a first-line antifungal agent for the treatment and prophylaxis of invasive candidiasis in pediatric patients. Pediatric patients are at risk of suboptimal drug exposure, due to developmental changes in gastrointestinal and renal function, metabolic capacity, and volume of distributio...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: van der Elst, Kim C. M., van Alst, Manouche, Lub-de Hooge, Marjolijn N., van Hateren, Kai, Kosterink, Jos G. W., Alffenaar, Jan-Willem C., Schölvinck, Elisabeth H.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249449/
https://ncbi.nlm.nih.gov/pubmed/25182638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03636-14
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