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In Vivo Efficacy of Apramycin in Murine Infection Models

Apramycin is a unique aminoglycoside with a dissociation of antibacterial activity and ototoxicity. We assessed the antibacterial efficacy of apramycin in two murine models of infection, Mycobacterium tuberculosis aerosol infection and Staphylococcus aureus septicemia. In both infection models, the...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Meyer, Martin, Freihofer, Pietro, Scherman, Michael, Teague, Joanne, Lenaerts, Anne, Böttger, Erik C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249428/
https://ncbi.nlm.nih.gov/pubmed/25136009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03239-14
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