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In Vivo Efficacy of Apramycin in Murine Infection Models

Apramycin is a unique aminoglycoside with a dissociation of antibacterial activity and ototoxicity. We assessed the antibacterial efficacy of apramycin in two murine models of infection, Mycobacterium tuberculosis aerosol infection and Staphylococcus aureus septicemia. In both infection models, the...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Meyer, Martin, Freihofer, Pietro, Scherman, Michael, Teague, Joanne, Lenaerts, Anne, Böttger, Erik C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249428/
https://ncbi.nlm.nih.gov/pubmed/25136009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03239-14
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