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Disruption of the Transcriptional Regulator Cas5 Results in Enhanced Killing of Candida albicans by Fluconazole

Azole antifungal agents such as fluconazole exhibit fungistatic activity against Candida albicans. Strategies to enhance azole antifungal activity would be therapeutically appealing. In an effort to identify transcriptional pathways that influence the killing activity of fluconazole, we sought to id...

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Publicado en:Antimicrob Agents Chemother
Main Authors: Vasicek, Erin M., Berkow, Elizabeth L., Bruno, Vincent M., Mitchell, Aaron P., Wiederhold, Nathan P., Barker, Katherine S., Rogers, P. David
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249418/
https://ncbi.nlm.nih.gov/pubmed/25182640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00064-14
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