Impact of Hypoalbuminemia on Voriconazole Pharmacokinetics in Critically Ill Adult Patients

Setting the adequate dose for voriconazole is challenging due to its variable pharmacokinetics. We investigated the impact of hypoalbuminemia (<35 g/liter) on voriconazole pharmacokinetics in adult intensive care unit (ICU) patients treated with voriconazole (20 samples in 13 patients) as well as...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Vanstraelen, Kim, Wauters, Joost, Vercammen, Ine, de Loor, Henriette, Maertens, Johan, Lagrou, Katrien, Annaert, Pieter, Spriet, Isabel
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249353/
https://ncbi.nlm.nih.gov/pubmed/25182655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03641-14
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